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Biotin—(acetyl-CoA-carboxylase) ligase : ウィキペディア英語版 | Biotin—(acetyl-CoA-carboxylase) ligase
In enzymology, a biotin-() ligase () is an enzyme that catalyzes the chemical reaction :ATP + biotin + apo-(ligase (ADP-forming) ) AMP + diphosphate + (ligase (ADP-forming) ) The 3 substrates of this enzyme are ATP, biotin, and apo-(ligase (ADP-forming) ), whereas its 3 products are AMP, diphosphate, and acetyl-CoA:carbon-dioxide ligase (ADP-forming). This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. This enzyme participates in biotin metabolism. This protein may use the morpheein model of allosteric regulation. == Nomenclature ==
The systematic name of this enzyme class is biotin:apo-(ligase (ADP-forming) ) ligase (AMP-forming). Other names in common use include: * biotin-(carboxylase ) synthetase, * biotin-(coenzyme A carboxylase ) synthetase, * acetyl coenzyme A holocarboxylase synthetase, * acetyl CoA holocarboxylase synthetase, * biotin:apocarboxylase ligase, * biotin holoenzyme synthetase, * and HCS.
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